根据美国外科学会ACOSOG Z4032/Z0030研究的定义整理如下：

局部复发（Local failure，local recurrence ）:

1.  原发灶邻近的肺组织，支气管残端，邻近支气管残端的肺门。[Adjacent lung parenchyma, bronchial stump, or in the hilum adjacent to the bronchial stump].

2.  以下用于局限性切除的病例，如肺楔形切除术。

2.1  复发位于原发肺叶的切除线 (局部进展，local progression)；[Recurrence within the primary tumor lobe at the staple line (local progression)]；

2.2  复发位于原发肺叶但远离切除线 (累及肺叶失败，involved lobe failure)[Recurrence within the primary tumor lobe away from the staple line (involved lobe failure)]

2.3  复发位于肺门淋巴结（Recurrence within hilar lymph nodes.） 

区域复发（Regional failure，Regional recurrence）:

1.  复发部位在与支气管残端不连续的肺门组织，纵隔，胸壁或者同侧胸膜；[hilum separate from bronchial stump, in the mediastinum, chest wall,or ipsilateral pleura].

2.  复发位于手术同侧其他肺叶，或者在同侧纵隔或者隆突下淋巴结。[defined as recurrence within another lobe on the same side as the resection or within ipsilateral mediastinal or subcarinal lymph nodes].

远处转移（Distant failure，Distant recurrence）:

1.  对侧胸腔，对侧纵隔或者肺门淋巴结，或者远处器官转移。（Distant recurrence was defined as recurrence within contralateral, mediastinal, or hilar lymph nodes or distant metastatic disease.）

校对；小全  2019年11月3日

【参考文献】

1.  Impact of Brachytherapy on Local Recurrence Rates After Sublobar Resection: Results From ACOSOG Z4032 (Alliance), a Phase III Randomized Trial for High-Risk Operable Non–Small-Cell Lung Cancer. JCO. VOLUME 32 NUMBER 23 AUGUST 10 2014